我希望如果应用程序在单个AppDomain中运行，则有一种避免自定义配置文件的方法。

解决方案

回答

来自Suzanne Cook的.NET CLR注意：

App.Config Files:
  
  As default  the app config file of the
  default appdomain is in the process
  exe’s directory and named the same as
  the process exe + ".config".  Also,
  note that a web.config file is an
  app.config - ASP.NET sets that as the
  config file for your appdomain.
  
  To change the config file, set an
  AppDomainSetup.ConfigurationFile to
  the new location and pass that
  AppDomainSetup to your call to
  AppDomain.CreateDomain(). Then, run
  all of the code requiring that
  application config from within that
  new appdomain.
  
  Note, though, that you won’t be able
  to choose the CLR version by setting
  the ConfigurationFile – at that point,
  a CLR will already be running, and
  there can only be one per process.
  
  Application configuration files are
  per appdomain. So, you can set a ‘dll
  config’ by using the method above, but
  that means that it will be used for
  the entire appdomain, and it only gets
  one.